WHO has been assessing this COVID-19 outbreak as a global health emergency. The easy spread of this virus posing enormous health, economic, environmental, and social challenges to the entire human population. This paper aims to provide an understanding of the incidence of epidemics of a disease such as the COVID-19 pandemic which is currently a concern of people around the world with a system thinking approach using a system dynamics method. The number cases of COVID-19 in DKI Jakarta will continue to increase if intervention is not carried out with exponential growth behavior. The total cost of care and medication without intervention is 3.4 trillion rupiah. In other hand, economic loss arising from restricting activity policy reached 415 billion rupiah. Meanwhile, the environmental impact also caused in this case is increasing medical waste in the environment reaching 45,200 tons.
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